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Clinician examining a woman's leg

Swollen calf - red flag symptoms

When does a swollen calf indicate deep vein thrombosis? What other causes should you consider?...

Jaundice eye

Jaundice - red flag symptoms

Which signs and symptoms are red flags that jaundice may have a serious cause?...

Tired all the time - red flag symptoms

Red flag symptoms, appropriate investigations in primary care, how to rule out serious pathology and...

Cervical lymphadenopathy - red flag symptoms

An overview of red flags in cervical lymphadenopathy including possible causes, investigations and w...

Patients with beta thalassaemia major will require monthly blood transfusions to avoid complications (Photograph: SPL)

Haematology - Thalassaemia

Diagnosis and treatment of thalassaemia and the role of the GP in its management, including the risk...

Blood film of a patient with sickle cell disease, with sickle cells, target cells and signs of hyposplenism (Photograph: Dr Patel)

Sickle cell anaemia

The diagnosis, features and management of sickle cell anaemia, including identifying and dealing wit...

Multiple myeloma

Clinical features, investigations, management and the GP's role in this rare haematological malignan...

Acute myeloid leukaemia: clinical review

Acute myeloid leukaemia (AML) is a clonal malignant disorder characterised by the accumulation of im...

Diffuse large B-cell lymphoma - Clinical review

An overview for GPs of the diagnosis, management and prognosis of this type of non-Hodgkin lymphoma....

Case study - Painful lumps on the legs

A four-month history of numerous lesions caused this patient concern....

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